• Product Name: Aicar
  • Appearance: White fine powder
  • Purity: 99% min
  • Package: Pack by foil bag
  • CAS No.: 2627-69-2

What Is Aicar

Aicar, with the full name of 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, is a substance naturally produced by the human body and an allosteric activator of activated protein kinase(AMPK) permeable to cells. Aicar supplement can regulate the metabolism of glucose and lipids, and inhibit the production of pro-inflammatory cytokines and iNOS. Aicar can enhance the proliferation, differentiation ad mineralization of osteoblasts MC3T3-EI, and attenuate the pro-inflammatory cytokines included by pschotropin in astrocytes. AMPK is a protein that regulates metabolism in many ways. AMPK acts as an energy regulator and is activated during exercise or other conditions that consume cellular energy. This bodybuilding supplement can increase the metabolic activity of tissues by changing the physical composition of muscles, thus becoming a potential drug for the treatment of diabetes. We can supply Aicar powder for bodybuilding, inquiry us for more details now.

  1. Many bodybuilders and athletes use Aicar peptide to improve their endurance and performance. At the same time, it has incredible fat burning ability.
  2. It is known for its incredible effects in improving endurance levels and burning fat. Many studies have shown that this peptide is often studied in mice, proving that it can induce metabolic genes. It can significantly improve the running endurance by converting fast-twitch fibers into fat-burning, more energy-efficient, and slow-twitch fibers to enhance endurance.
  3. It is used clinically to treat and prevent ischemic heart injury.
  4. It can reduce the frequency and size of human myocardial infarctions by up to 25%.
  5. Pharmacological activation of AMPK by Aicar can reduce heart tissue damage and protect the mitochondrial structure in cardiomyocytes.
  6. It has a powerful ability to treat human metabolic disorders and diseases, such as, diabetes.
  7. It can greatly improve the performance, compared with the traditional endurance performance, the performance increase is as high as 40-50%.

The nucleoside form is an adenosine analog that can enter cardiomyocytes to inhibit adenosine kinase and adenosine deaminase. Only in the case of myocardial ischemia, it can increase the rate of nucleotide resynthesis, thereby increasing the production of adenosine monophosphate. In cardiomyocytes, acadesine is phosphorylated to Aicar to activate AMPK without changing the level of nucleotides. Once activated by Aicar, AMPK will strive to make the energy more usable. It can increase the use fat for energy and cause the cell to produce more mitochondria, which is the cell’s power source or energy creator. AMPK basically ensures that various tissues in the body will not run out of energy. Although the metabolic processes of body are strongly stimulated, the powder can greatly improve performnce, up to an incredible 40-50% compared to traditional endurance.

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