What Is L-alanine
L-alinine is the L-enantiomer of alanine, which acts as a diaminopropionic acid ammonia lyase inhibitor and an essential metabolite. L-alanine is one of the 22 proteinogenic amino acids, the building blocks of proteins. It is generally classified as a nonpolar amino acids. As an isoform that is incorporated into proteins, it is second only to amine groups in occurrence, accounting for 7.8% of carboxylic acid groups in the 1150 methyl sample. It is colorless to white crystalline powder, soluble in water and ethanol, insoluble in ether and acetone. L-alanine is mainly used in biochemical research, tissue culture, liver function test, flavor enhancer., etc.
What Is L-alanine Used For
L-alanine is an amino acid. Amino acids are important in all aspects of maintaining the body, especially in building muscle and synthesizing protein. It helps support the immune system and also helps metabolize acids and sugar from organic sources.
- L-alanine is an important raw material for the synthesis of Vitamin B6.
- The injection with L-alanine as the main component can mainly treat liver, encephalopathy, and promote the rapid recovery of patients with hepatic coma. It is also a good diuretic medicine.
- Blood sugar regulation. Our bodies are constantly receiving and releasing glucose, which allows us to maintain healthy blood sugar levels. But for those with hypoglycemia don’t produce enough blood sugar, additional supplementation of L-alanine can stabilize blood glucose levels in diabetic mice. L-alanine is a crystalline free amino acid that is highly concentrated in muscle tissue. The liver can convert L-alanine into glucose that muscles need. It also helps metabolize glucose into energy. Without L-alanne, it would be impossible for the body to convert glucose into energy. Although alanine is considered a nonessential acid, meaning it is produced naturally in the body, supplementing with L-alanine is very important. For that it can help the liver flush out harmful toxins from the body and maintain healthy blood sugar levels.
- Helps with prostate disease. Alanine is also present in prostatic fluid. This suggests that alanine may be able to prevent enlarged prostate. This condition often results in frequent and painful urination. It can also cause urinary retention. When combined with glycine and glutamic acid, alanine can shrink the prostate gland and relieve nocturia, frequency and urgency. Another study showed that alanine can inhibit the metabolism of prostate cancer cells.
- Improve the body’s immunity. Not only is alanine one of the many building blocks of protein, but is also helps metabolize tryptophan(an amino acid that our bodies don’t produce naturally). Without tryptophan, our bodies can’t make serotonin. A lack of serotonin can lead to symptoms such as depression, mood swings and insomnia.
- Prevent the formation of kidney stones. Alanine also helps lower cholesterol and neutralizes the insoluble toxins that cause kidney stones, especially helpful for people with a family history of kidney stone disease.
- Used in beverages to relieve sour, after-bitter and other peculiar smells. It can also reduce the irritation caused by bad tastes, improve the full mouthfeel and the complexity of the taste, prolong the aftertaste.
- Used in condiments. L-alanine has a cool and sweet feeling. Its molecular weight is small, and it tastes quickly in the mouth. Therefore, it can cover up the stimulation of food entrance, making the taste more mellow and full.
- Its sweetness is 1.2 times that of sucrose, which has the effect of improving freshness and flavor. Improving the taste of artificial synthetic sweeteners can increase the sweetness and reduce the dosage.
- Nutritional supplements for health food and beverages. In various foods and beverages, adding L-alanine can obviously improve the protein utilization rate in foods and beverages.
- Alanine has the characteristics of being directly absorbed by cells. So it can supplement the amino acids needed by the human body, provide nutrition, and enhance physical fitness. It can also meet energy needs and quickly restore muscle metabolism. In addition, it can also reduce ketosis caused by intense aerobic exercise, which is conducive to the recovery of the body after exercise and boosts the spirit.
- During more intense workouts, L-alanine is quickly distributed throughout the body, such as the muscles. Taking L-alanine before a big workout can increase energy levels and the duration of your workout. Additionally, alanine can prevent the release of toxins when muscles break down, allowing for faster recovery as well.
How Does L-alanine Work in Bodybuilding
When we consume protein, our muscles absorb and synthesize the amino acids in it. Our muscles break down these amino acids to use them and repair damaged tissue. Alanine is one of the amino acids our muscles use to repair themselves. But our muscles don’t just break down alanine to repair degraded muscle tissue. Sometimes, our bodies use alanine as fuel when there isn’t enough fat stored for energy.
L-alanine causes the body to go through an additional metabolic process. During this cycle, our muscles metabolize alanine from the blood, converting it to pyruvate. Pyruvate is a carbon compound that is converted to glucose during gluconeogenesis. At the end of these cycles, alanine has been converted to glucose an can function in a number of ways. When we exercise or don’t eat, our bodies naturally burn muscle for energy. However, with alanine, the body can use energy without relying on muscles.
More About L-alanine
It is usually found in many protein foods, like: poultry such as chicken and turkey, grass-fed beef and meat, fish and seafood, eggs, soy products, yeast, whole grains such as wheat germ, quinoa, rice, buckwheat, oats, etc.
In powder form, the recommended amount of alanine is 1.1 to 2.3g per day. Take between meals or as recommended by your healthcare professional.
Doses of 20 to 40g per day can be safely used to help control blood sugar levels in people with diabetes, such as preventing low blood sugar caused by too much insulin. If treating another condition, such as high cholesterol, it is best to consult professional doctors.
- Mainly use L-aspartic acid as raw material, after decarboxylation, enzyme killing, decolorization, filtration, crystallization, centrifugation, washing, drying to get L-alanine powder.
- It involves culturing Brevibacterium or Corynebacterium mutants that require D-alanine for growth on a medium containing digestible carbon, nitrogen sources, inorganic salts, and microbial growth stimulants until accumulation of L-alanine, followed by separation to obtain L-alanine powder.